Category:LBS: Difference between revisions

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|+ Table 1. Common Categories
|+ Table 1. Common Categories
|-
|-
! Common Name || Sequence || LipidBank ID
! Common Name || Sequence
|-
|-
|colspan="3" style="background:#efefef; text-align:center"| By GalCer Synthase (EC 2.4.1.62)
|colspan="2" style="background:#efefef; text-align:center"| By GalCer Synthase (EC 2.4.1.62)
{{#repeat:LBS/AbbrevTable/Row|1|
{{#repeat:LBS/AbbrevTable/Row|1|
Gala Gala1-4Galb1-Cer LBSF2.
Gala_(Ga) Gala1-4/6Galb1-Cer LBSF2.
Spirometo Galb1-4Glcb1-3Galb1-Cer LBSFG5
Spirometo_(Sp) Galb1-4Glcb1-3Galb1-Cer LBSFG5
}}
}}
|-
|-
|colspan="3" style="background:#efefef; text-align:center"| By GlcCer Synthase (EC 2.4.1.80)
|colspan="2" style="background:#efefef; text-align:center"| By GlcCer Synthase (EC 2.4.1.80)
{{#repeat:LBS/AbbrevTable/Row|1|
{{#repeat:LBS/AbbrevTable/Row|1|
Ganglio GalNAcb1-4Galb1-4Glcb1-Cer LBSZ8.
Ganglio_(Gg) GalNAcb1-4Galb1-4Glcb1-Cer LBSZ8.
Isoganglio GalNAcb1-3Galb1-4Glcb1-Cer LBSZ7.
Isoganglio_(iGg) GalNAcb1-3Galb1-4Glcb1-Cer LBSZ7.
Globo Gala1-4Galb1-4Glcb1-Cer LBSZ2.
Globo_(Gb) Gala1-4Galb1-4Glcb1-Cer LBSZ2.
Isoglobo Gala1-3Galb1-4Glcb1-Cer LBSZ1.
Isoglobo_(iGb) Gala1-3Galb1-4Glcb1-Cer LBSZ1.
Lacto Galb1-3GlcNAcb1-3Galb1-4Glcb1-Cer LBSZD4
Lacto_(Lc) Galb1-3GlcNAcb1-3Galb1-4Glcb1-Cer LBSZD4
NeoLacto Galb1-4GlcNAcb1-3Galb1-4Glcb1-Cer LBSZA5
NeoLacto_(nLc) Galb1-4GlcNAcb1-3Galb1-4Glcb1-Cer LBSZA5
Muco Galb1-4Galb1-4Glcb1-Cer LBSZ5.
Muco_(Mc) Galb1-4Galb1-4Glcb1-Cer LBSZ5.
}}
}}
|-
|-
|colspan="3" style="background:#efefef; text-align:center"| With Mannose
|colspan="2" style="background:#efefef; text-align:center"| With Mannose
{{#repeat:LBS/AbbrevTable/Row|1|
{{#repeat:LBS/AbbrevTable/Row|1|
Arthro GlcNAcb1-3Manb1-4Glcb1-Cer LBSY
Arthro_(At) GlcNAcb1-3Manb1-4Glcb1-Cer LBSY
Mollu Mana1-3Manb1-4Glcb1-Cer LBSGMM
Mollu_(Mu) Mana1-3Manb1-4Glcb1-Cer LBSGMM
}}
}}
|}
|}

Revision as of 13:11, 6 June 2012

Sphingolipid

Class Overview

Sphingosine & Ceramide

Sphingosine is synthesized from decarboxylating condensation of palmitoyl CoA with serine. It is a 18-carbon amino alcohol (16 carbons from palmitic acid and 2 from serine) with one unsaturated bond (2-amino-4-octadecene-1,3-diol). Sphingosine is further acylated to form ceramide, an important component of cell membranes.
The Sphingolipid category (LBS) in this database includes glycosphingolipid, phosphosphingolipid, and ceramide.

スフィンゴシンはパルミトイルCoAがアミノ酸セリンと脱炭酸縮合して生成します。炭素を18個含むアミノアルコール(16個がパルミチン酸、2個がセリン由来)で不飽和結合を1つ含んでいます (2-amino-4-octadecene-1,3-diol)。 スフィンゴシンがアシル化したものが、細胞膜の重要な成分であるセラミドです。
このデータベースにおけるスフィンゴ脂質カテゴリー (LBS) には、スフィンゴ糖脂質 (glycosphingolipid)、スフィンゴリン脂質 (phosphosphingolipid) 、セラミド (ceramide) が含まれています。

Sphingolipid Overview

Glycosphingolipid
スフィンゴ糖脂質

Phosphosphingolipid
スフィンゴリン脂質

Glycosphingolipid スフィンゴ糖脂質

Common Abbreviations

Page/ID Design for Sphingolipid

L B S s1 s2 s3 n1 n2 d y c1 c2

  • s1 ∼ s3 ... Structure code (3 digits)
Explained below
  • n1, n2 ... the number of sugars (2 digits)
  • d ... distribution (Vertebrate; Invertebrate; N both; Plant; Chemical synthesis) (1 digit)
  • y ... the number of sialic acids ( 1 digit)
  • c1, c2 ... serial numbers

  • s1 ∼ s3 ... 構造コード (3桁）
下に詳述
  • n1, n2 ... 糖の数 (2桁)
  • d ... 分布 (V 脊椎; I 無脊椎; N 両方; P 植物; C 合成品) (1桁)
  • y ... シアル酸の数 (1桁)
  • c1, c2 ... 通し番号

Structure Code

code Galactose
0 no sugar
1 Galactose
(α form) 		Galα1-3 ...
2 Galα1-4 ...
3 Galα1-6 ...
4 Galactose
(β form) 		Galβ1-3 ...
5 Galβ1-4 ...
6 Galβ1-6 ...
code N-Acetylated Sugars
7 N-Acetyl Galactosamine
(β form) 		GalNAcβ1-3 ...
8 GalNAcβ1-4 ...
9 GalNAcβ1-6 ...
A N-Acetyl Glucosamine
(β form) 		GlcNAcβ1-3 ...
B GlcNAcβ1-4 ...
C GlcNAcβ1-6 ...


code Galactose & Glucose
D Aminated Sugars
(Except for Code 7∼C) 		GalNAc, GalN
E GlcNAc, GlcN
F Galactose
(Except Code 1∼6) 		Gal
G Glucose Glc
code Other Sugars
J Inositol (Ins)
K Fucose (Fuc)
L Pentose sugars
(Ara, Xyl)
M Mannose and Rhamnose (= 6-deoxymannose)
(Man, Rha)
N Neuraminic acids
(NeuAc, NeuNH, NeuGc, KDN)
code Modifiers
P Phosphate (HPO4), Sulphate (HSO4),
and Phosphocholine (PC)
Q Aminoethylphosphates
AEPn, MAEPr, EtnP
R Alkyl and acyl groups
OAc, Methyl, Butenyl
code Abbreviations
Y GlcNAcβ1-3Manβ1-4Glcβ1-1Cer
Z Galβ1-4Glcβ1-1bCer



Common Patterns

Table 1. Common Categories
Common Name Sequence
By GalCer Synthase (EC 2.4.1.62)
Gala_(Ga) 0 Galα1-4/6Galβ1-Cer
Spirometo_(Sp) 0 Galβ1-4Glcβ1-3Galβ1-Cer
By GlcCer Synthase (EC 2.4.1.80)
Ganglio_(Gg) 0 GalNAcβ1-4Galβ1-4Glcβ1-Cer
Isoganglio_(iGg) 0 GalNAcβ1-3Galβ1-4Glcβ1-Cer
Globo_(Gb) 0 Galα1-4Galβ1-4Glcβ1-Cer
Isoglobo_(iGb) 0 Galα1-3Galβ1-4Glcβ1-Cer
Lacto_(Lc) 0 Galβ1-3GlcNAcβ1-3Galβ1-4Glcβ1-Cer
NeoLacto_(nLc) 0 Galβ1-4GlcNAcβ1-3Galβ1-4Glcβ1-Cer
Muco_(Mc) 0 Galβ1-4Galβ1-4Glcβ1-Cer
With Mannose
Arthro_(At) 0 GlcNAcβ1-3Manβ1-4Glcβ1-Cer
Mollu_(Mu) 0 Manα1-3Manβ1-4Glcβ1-Cer

Classification

By the Number of Sugars

Table 1. Classification by the Number of Sugars
# of sugars Verbebrates (0 items) Invertebrate (0 items)
1  
(0 pages)		  
(0 pages)
2  
(0 pages)		  
(0 pages)
3  
(0 pages)		  
(0 pages)
4  
(0 pages)		  
(0 pages)
5  
(0 pages)		  
(0 pages)
6  
(0 pages)		  
(0 pages)
7  
(0 pages)		  
(0 pages)
8  
(0 pages)		  
(0 pages)
9  
(0 pages)		  
(0 pages)
10-19  
(0 pages)		  
(0 pages)
20-29  
(0 pages)		  
(0 pages)

By the Number of Sialic acids

Table 2. Classification by the Number of Sialic acids
# of sialic acids Verbebrates (0 items) Invertebrate (0 items)
1  
(0 pages)		  
(0 pages)
2  
(0 pages)		  
(0 pages)
3  
(0 pages)		  
(0 pages)
4  
(0 pages)		  
(0 pages)
5  
(0 pages)		  
(0 pages)
6  
(0 pages)		  
(0 pages)
7  
(0 pages)		  
(0 pages)
8  
(0 pages)		  
(0 pages)

Subcategories

This category has the following 4 subcategories, out of 4 total.

L

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