LBF20303TX01

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Fatty acid (脂肪酸)

Glycerolipid (グリセロ脂質)

Sphingolipid (スフィンゴ脂質)

Journals (雑誌一覧)

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Upper classes: LB LBF

IDs and Links
LipidBank	XPR2002
LipidMaps	LMFA03030005
CAS
KEGG	{{{KEGG}}}
KNApSAcK	{{{KNApSAcK}}}
mol	LBF20303TX01

THROMBOXANE A3
Structural Information
Systematic Name	7- [ 3- (3 (S) -Hydroxy-1 (E) ,5 (Z) -octadienyl) -1 (S) ,5 (S) ,4,6-dioxabicyclo [ 3.1.1 ] hept-2-yl ] -5 (Z) -heptenoic acid
Common Name	THROMBOXANE A3 7- [ 3- (3 (S) -Hydroxy-1 (E) ,5 (Z) -octadienyl) -1 (S) ,5 (S) ,4,6-dioxabicyclo [ 3.1.1 ] hept-2-yl ] -5 (Z) -heptenoic acid
Symbol	TXA3
Formula	C21H32O4
Exact Mass	348.23005951199997
Average Mass	348.47637999999995
SMILES	C([C@H]([C@H](C=C[C@H](O)CC=CCC)2)[C@@H](C1)O[C@H](C2)1)C=CCCCC(O)=O
Physicochemical Information
Melting Point
Boiling Point
Density
Optical Rotation
Refractive Index
Solubility
Source
Chemical Synthesis
Metabolism	Prostaglandin H3 is produced from 5,8,11,14,17-eicosapentaenoic acid, which is one-eighth as efficient a substrate as arachidonic acid, by the catalysis of fatty acid cyclooxygenase, and then transformed to unstable thromboxane A3 Needleman_P et al., which is converted non-enzymatically to stable thromboxane B3.
Biological Activity	Thromboxane A3 did not cause platelet aggregation unlike thromboxane A2, and inhibited platelet aggregation by other agonists Needleman_P et al..
Genetic Information
Note
Spectral Information
Mass Spectra
UV Spectra
IR Spectra
NMR Spectra
Other Spectra
Chromatograms

Reported Metabolites, References
Biospecies ID Compound Name Reference Comment n.a. LBF20303TX01 See above. Needleman_P et al. 1979