LBF20406AM27: Difference between revisions

Revision as of 07:32, 28 May 2010

Upper classes: LB LBF

N-Hydroxy-N-arachidonoylamide

Structural Information
	N-Hydroxy-N-arachidonoylamide
	N-Hydroxy-N-arachidonoylamide

Formula	C20H33NO2
Exact Mass	319.251129305
Average Mass	319.48156
SMILES	`C(CC=CCC=CCC=CCC=CCCCC(NO)=O)CCC`
Physicochemical Information
	colorless oil Sheskin_T et al.






	This compound was synthesized from arachidonoyl chloride and hydroxylamine hydrochloride.Yield 49%. Sheskin_T et al.

	Binding to the brain cannabinoid receptor (CBl), Ki (nM)>1000 Sheskin_T et al.


Spectral Information
Mass Spectra
UV Spectra
IR Spectra
NMR Spectra	¹H NMR (CDCl3) δ 5.30-5.43 (m, 8H), 2.78-2.86 (m, 6H), 2.02-2.17 (m, 6H), l.70-1.78(m, 2H), 1.22-1.38 (m, 6H), 0.89 (t, J=6.9 Hz, 3H). Sheskin_Tet al.
Other Spectra
Chromatograms

Reported Metabolites, References

Biospecies	ID	Compound Name	Reference	Comment
n.a.	LBF20406AM27	See above.	Sheskin_T et al. 1997

@@ Line 6: / Line 6: @@
 |LipidBank=XPR7043
 |LipidMaps=LMFA08020029
-|SysName=N-hydroxy -N-arachidonoyl amide
+|SysName=N-Hydroxy-N-arachidonoylamide
-|Common Name=&&N-hydroxy -N-arachidonoyl amide&&
+|Common Name=&&N-Hydroxy-N-arachidonoylamide&&
 |Melting Point=colorless oil [[Reference:Sheskin_T:Hanus_L:Slager_J:Vogel_Z:Mechoulam_R:,J. Med. Chem.,1997,40,659|{{RelationTable/GetFirstAuthor|Reference:Sheskin_T:Hanus_L:Slager_J:Vogel_Z:Mechoulam_R:,J. Med. Chem.,1997,40,659}}]]
 |NMR Spectra=^1 H NMR (CDCl3)  delta 5.30-5.43 (m, 8H), 2.78-2.86 (m, 6H), 2.02-2.17 (m, 6H), l.70-1.78(m, 2H), 1.22-1.38 (m, 6H), 0.89 (t, J=6.9 Hz, 3H). [[Reference:Sheskin_T:Hanus_L:Slager_J:Vogel_Z:Mechoulam_R:,J. Med. Chem.,1997,40,659|{{RelationTable/GetFirstAuthor|Reference:Sheskin_T:Hanus_L:Slager_J:Vogel_Z:Mechoulam_R:,J. Med. Chem.,1997,40,659}}]]