LBF20406SC01: Difference between revisions
No edit summary |
No edit summary |
||
| Line 12: | Line 12: | ||
|Density=0.9082 at 20 °C | |Density=0.9082 at 20 °C | ||
|Refractive=1.4824 at 20 °C | |Refractive=1.4824 at 20 °C | ||
|Solubility=soluble in acetone, methyl alcohol, ether and petroleum ether. | |Solubility=soluble in acetone, methyl alcohol, ether and petroleum ether.<!--0224--><!--0225--><!--0328--><!--0347--> | ||
|Source=Constituent of many animal phospholipids, also of some ferns and mosses. Confinded to fats of land animals; brain, liver, glandular and egg lipids. | |Source=Constituent of many animal phospholipids, also of some ferns and mosses. Confinded to fats of land animals; brain, liver, glandular and egg lipids. | ||
|Chemical Synthesis= | |Chemical Synthesis= | ||
Revision as of 16:30, 26 January 2010
| LipidBank Top (トップ) |
Fatty acid (脂肪酸) |
Glycerolipid (グリセロ脂質) |
Sphingolipid (スフィンゴ脂質) |
Journals (雑誌一覧) |
How to edit (ページの書き方) |
| IDs and Links | |
|---|---|
| LipidBank | DFA0213 |
| LipidMaps | LMFA01030001 |
| CAS | |
| KEGG | {{{KEGG}}} |
| KNApSAcK | {{{KNApSAcK}}} |
| mol | LBF20406SC01 |
| Arachidonic acid | |
|---|---|
| |
| Structural Information | |
| 5, 8, 11, 14-Eicosatetraenoic acid / 5, 8, 11, 14-icosatetraenoic acid | |
| |
| AA / Ara / C20:4n-6 / C20:4w6 | |
| Formula | C20H32O2 |
| Exact Mass | 304.240230268 |
| Average Mass | 304.46688 |
| SMILES | C(CC=CCC=CCC=CCC=CCCCC(O)=O)CCC |
| Physicochemical Information | |
| -49.5 °C | |
| 163 °C at 1 mmHg | |
| 0.9082 at 20 °C | |
| 1.4824 at 20 °C | |
| soluble in acetone, methyl alcohol, ether and petroleum ether. | |
| Constituent of many animal phospholipids, also of some ferns and mosses. Confinded to fats of land animals; brain, liver, glandular and egg lipids. | |
| Metabolic product of linoleic acid (9,12-18:2). The synthesis of 5,8,11,14-20:4 occurs via the following reaction sequence in the endoplasmic reticulum Sprecher_H et al.: 9,12-18:2 --> 6,9,12-18:3 --> 8,11,14-20:3 --> 5,8,11,14-20:4. | |
| There are two groups of essential fatty acids, the n-6 (or w6) and the n-3 (or w3). Arachidonic acid is n-6 fatty acids. Essential fatty acid deficiency causes skin lesion and growth retardation. Dietary supplementation of either linoleate, g-linoleate or arachidonate prevents such symptoms completely. The n-6 essential fatty acids have at least four roles Horrobin_DF : 1) Modulation of membrane structure. 2) Formation of bioactive molecules called eicosanoids. Arachidonic acid, which is nomally found esterifing sn-2 position of phospholipids, is released by the action of phospholipase A2. Free arachidonate is used for precursors of eicosanoids, such as PG2 series of prostaglandins, leukotrienes and thromboxanes. 3) Control of the water impermeability of the skin. 4) Regulation of cholesterol synthesis and transport. | |
| Spectral Information | |
| Mass Spectra | |
| UV Spectra | |
| IR Spectra | |
| NMR Spectra | |
| Other Spectra | |
| Chromatograms | |
| Reported Metabolites, References | |||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
|
