LBF20407HO02: Difference between revisions
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|Chemical Synthesis= | |Chemical Synthesis= | ||
|Metabolism= | |Metabolism= | ||
|Symbol=5(S),15(S)-DiHETE | |||
|Biological Activity=5(S),15(S)-DiHETE potentiates the degranulation of human polymorphonuclear leukocytes in response to platelet activating factor, but not f-Met-Leu-Phe, calcium ionophore A23187, or Leukotriene B 4 [[Reference:OFlaherty_JT:Thomas_MJ:,Prostaglandins Leukot. Med.,1985,17,199|{{RelationTable/GetFirstAuthor|Reference:OFlaherty_JT:Thomas_MJ:,Prostaglandins Leukot. Med.,1985,17,199}}]]. 5(S),15(S)-DiHETE is chemotactic for eosinophils with an ED<SUB><FONT SIZE=-1>5</FONT></SUB><SUB><FONT SIZE=-1>0</FONT></SUB> of 0.3 <FONT FACE="Symbol">m</FONT>M[[Reference:Morita_E:Schroder_JM:Christophers_E:,J. Immunol.,1990,144,1893|{{RelationTable/GetFirstAuthor|Reference:Morita_E:Schroder_JM:Christophers_E:,J. Immunol.,1990,144,1893}}]]. | |||
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{{Lipid/Footer}} | {{Lipid/Footer}} |
Revision as of 21:00, 6 January 2010
LipidBank Top (トップ) |
Fatty acid (脂肪酸) |
Glycerolipid (グリセロ脂質) |
Sphingolipid (スフィンゴ脂質) |
Journals (雑誌一覧) |
How to edit (ページの書き方) |
IDs and Links | |
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LipidBank | DFA8104 |
LipidMaps | - |
CAS | |
KEGG | {{{KEGG}}} |
KNApSAcK | {{{KNApSAcK}}} |
mol | LBF20407HO02 |
5S,15S-dihydroxy-6E,8Z,10Z,13E-eicosatetraenoic acid | |
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Structural Information | |
5S,15S-dihydroxy-6E,8Z,10Z,13E-eicosatetraenoic acid | |
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5(S),15(S)-DiHETE | |
Formula | C20H32O4 |
Exact Mass | 336.23005951199997 |
Average Mass | 336.46567999999996 |
SMILES | C(CCC(C=CCC=CC=CC=CC(CCCC(O)=O)O)O)CC |
Physicochemical Information | |
5(S),15(S)-DiHETE is synthesized by 15-lipoxygenase from 5(S)-HETE Green_FA . | |
5(S),15(S)-DiHETE potentiates the degranulation of human polymorphonuclear leukocytes in response to platelet activating factor, but not f-Met-Leu-Phe, calcium ionophore A23187, or Leukotriene B 4 OFlaherty_JT et al.. 5(S),15(S)-DiHETE is chemotactic for eosinophils with an ED50 of 0.3 mM Morita_E et al.. | |
Spectral Information | |
Mass Spectra | |
UV Spectra | lmax: 243nm e: 33,500 |
IR Spectra | |
NMR Spectra | |
Other Spectra | |
Chromatograms |
Reported Metabolites, References | ||||||||||||||||||||
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