LBF20503HO01: Difference between revisions
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|SysName=8R-hydroxy-5Z,9E,11Z,14Z,17Z-Eicosapentaenoic acid | |SysName=8R-hydroxy-5Z,9E,11Z,14Z,17Z-Eicosapentaenoic acid | ||
|Common Name=&&8R-hydroxy-5Z,9E,11Z,14Z,17Z-Eicosapentaenoic acid&& | |Common Name=&&8R-hydroxy-5Z,9E,11Z,14Z,17Z-Eicosapentaenoic acid&& | ||
|UV Spectra= | |UV Spectra=lambdamax: 236nm epsilon: 23,000 | ||
|Source=(±)8-HEPE is the major eicosanoid extract from the barnacle, E. modestus. <!--8146-->. | |Source=(±)8-HEPE is the major eicosanoid extract from the barnacle, E. modestus. <!--8146-->. | ||
|Chemical Synthesis= | |Chemical Synthesis= | ||
|Metabolism= | |Metabolism= | ||
|Symbol=(±)8-HEPE | |Symbol=(±)8-HEPE | ||
|Biological Activity=(±)8-HEPE causes barnacle eggs to hatch with an | |Biological Activity=(±)8-HEPE causes barnacle eggs to hatch with an IC_5 _0 = 2.4 x 10^- ^6 M [[Reference:Shing_TKM:Gibson_KH:Wiley_JR:Watt_lF:,Tetrahedron Lett.,1994,35,1067|{{RelationTable/GetFirstAuthor|Reference:Shing_TKM:Gibson_KH:Wiley_JR:Watt_lF:,Tetrahedron Lett.,1994,35,1067}}]]. Reports conflict as to whether the barnacle hatching activity is a result of the 8(R)-or the 8(S)-enantiomer <!--8146-->[[Reference:Shing_TKM:Gibson_KH:Wiley_JR:Watt_lF:,Tetrahedron Lett.,1994,35,1067|{{RelationTable/GetFirstAuthor|Reference:Shing_TKM:Gibson_KH:Wiley_JR:Watt_lF:,Tetrahedron Lett.,1994,35,1067}}]][[Reference:Hill_EM:Holland_DL:,Proc. Biol. Sci.,1992,247,41|{{RelationTable/GetFirstAuthor|Reference:Hill_EM:Holland_DL:,Proc. Biol. Sci.,1992,247,41}}]]. Apparently, only the 8(R)-HEPE induces oocyte maturation in the starfish [[Reference:Shing_TKM:Gibson_KH:Wiley_JR:Watt_lF:,Tetrahedron Lett.,1994,35,1067|{{RelationTable/GetFirstAuthor|Reference:Shing_TKM:Gibson_KH:Wiley_JR:Watt_lF:,Tetrahedron Lett.,1994,35,1067}}]]. | ||
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{{Lipid/Footer}} | {{Lipid/Footer}} |
Revision as of 14:00, 19 February 2010
LipidBank Top (トップ) |
Fatty acid (脂肪酸) |
Glycerolipid (グリセロ脂質) |
Sphingolipid (スフィンゴ脂質) |
Journals (雑誌一覧) |
How to edit (ページの書き方) |
IDs and Links | |
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LipidBank | DFA8119 |
LipidMaps | LMFA03070002 |
CAS | |
KEGG | {{{KEGG}}} |
KNApSAcK | {{{KNApSAcK}}} |
mol | LBF20503HO01 |
8R-hydroxy-5Z,9E,11Z,14Z,17Z-Eicosapentaenoic acid | |
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Structural Information | |
8R-hydroxy-5Z,9E,11Z,14Z,17Z-Eicosapentaenoic acid | |
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(±)8-HEPE | |
Formula | C20H30O3 |
Exact Mass | 318.21949482599996 |
Average Mass | 318.4504 |
SMILES | C(CC=CCC=CC=C[C@@H](CC=CCCCC(O)=O)O)=CCC |
Physicochemical Information | |
(±)8-HEPE is the major eicosanoid extract from the barnacle, E. modestus. . | |
(±)8-HEPE causes barnacle eggs to hatch with an IC_5 _0 = 2.4 x 10^- ^6 M Shing_TKM et al.. Reports conflict as to whether the barnacle hatching activity is a result of the 8(R)-or the 8(S)-enantiomer Shing_TKM et al. Hill_EM et al.. Apparently, only the 8(R)-HEPE induces oocyte maturation in the starfish Shing_TKM et al.. | |
Spectral Information | |
Mass Spectra | |
UV Spectra | lambdamax: 236nm ε: 23,000 |
IR Spectra | |
NMR Spectra | |
Other Spectra | |
Chromatograms |
Reported Metabolites, References | |||||||||||||||
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