LBF20107PG10

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Fatty acid (脂肪酸)

Glycerolipid (グリセロ脂質)

Sphingolipid (スフィンゴ脂質)

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Upper classes: LB LBF

IDs and Links
LipidBank	XPR1736
LipidMaps	LMFA03010054
CAS
KEGG	{{{KEGG}}}
KNApSAcK	{{{KNApSAcK}}}
mol	LBF20107PG10

11-deoxy Prostaglandin E1
Structural Information
Systematic Name	9-Oxo-15S-hydroxy-prosto-13E-en-1-oic acid
Common Name	11-deoxy Prostaglandin E1
Symbol
Formula	C20H34O4
Exact Mass	338.24570957599997
Average Mass	338.48156
SMILES	C(CC[C@@H](O)C=C[C@H]([C@H]1CCCCCCC(O)=O)CCC(=O)1)CC
Physicochemical Information
Melting Point
Boiling Point
Density
Optical Rotation
Refractive Index
Solubility
Source
Chemical Synthesis
Metabolism
Biological Activity	11-deoxy Prostaglandin E1 shows spieces and subtype dependent EP agonistic effect. In guinea pig, 11-deoxy Prostaglandin E1 induce bronchodilation and vasodepression. Hall_DW et al. 11-deoxy Prostaglandin E1 is reported to increase cAMP release via EP receptors in Jurkat cells. De_Vries_GW et al. The Ki value of each murine EPs is 600 nM (EP1), 45 nM (EP2), 1.1 nM (EP3), 23 nM (EP4) . Kiriyama_M et al. 11-deoxy Prostaglandin E1, a selective EP2/EP3/EP4 agonist, inhibites IL-1beta-induced IL-6 production in human gingival fibroblast. Noguchi_K et al. 11-deoxy Prostaglandin E1 stimulates K secretion through EP2 receptors at EC50 values of 8.3 nM in guinea pig distal colonic mucosa . Halm_DR et al.
Genetic Information
Note
Spectral Information
Mass Spectra
UV Spectra
IR Spectra
NMR Spectra
Other Spectra
Chromatograms

Reported Metabolites, References
Biospecies ID Compound Name Reference Comment n.a. LBF20107PG10 See above. De_Vries_GW et al. 1995 n.a. LBF20107PG10 See above. Hall_DW et al. 1976 n.a. LBF20107PG10 See above. Halm_DR et al. 2001 n.a. LBF20107PG10 See above. Kiriyama_M et al. 1997 n.a. LBF20107PG10 See above. Noguchi_K et al. 2002