LBF20307HO01
LipidBank Top (トップ) |
Fatty acid (脂肪酸) |
Glycerolipid (グリセロ脂質) |
Sphingolipid (スフィンゴ脂質) |
Journals (雑誌一覧) |
How to edit (ページの書き方) |
IDs and Links | |
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LipidBank | DFA8144 |
LipidMaps | LMFA03050007 |
CAS | |
KEGG | {{{KEGG}}} |
KNApSAcK | {{{KNApSAcK}}} |
mol | LBF20307HO01 |
15S-hydroxy-8Z,11Z,13E-eicosatrienoic acid | |
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Structural Information | |
15S-hydroxy-8Z,11Z,13E-eicosatrienoic acid | |
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15(S)-HETrE | |
Formula | C20H34O3 |
Exact Mass | 322.25079495399996 |
Average Mass | 322.48216 |
SMILES | C(CCC(C=CC=CCC=CCCCCCCC(O)=O)O)CC |
Physicochemical Information | |
15(S)-HETrE is a hydroxy fatty acid derived from dihomo-gamma-linolenic acid. | |
Compared to a series of hydroxypolyenoic fatty acids, 15(S)-HETrE is a more potent inhibitor of human 5-lipoxygenase from polymorphonuclear leukocytes having an IC_5 _0 of 4.6muM at an arachidonic acid concentration of 5 muM Petrich_K et al.. In rat basophilic leukemia cell lysates, 15(S)-HETrE inhibits 5-lypoxygenase with an IC_5 _0 of 77muM (arachidonic acid concentration of 60muM) Haviv_F et al.. 15(S)-HETrE is 10- to 20-fold less potent than 15(S)-HETE and 15(S)-HpETE under these experimental conditions Haviv_F et al.. | |
Spectral Information | |
Mass Spectra | |
UV Spectra | lambdamax: 235nm ε: 23,000 |
IR Spectra | |
NMR Spectra | |
Other Spectra | |
Chromatograms |
Reported Metabolites, References | |||||||||||||||
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