LBF20406HO07

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Upper classes: LB LBF



5S,6R-dihydroxy-7E,9E,11Z,14Z-eicosatetraenoic acid
LBF20406HO07.png
Structural Information
5S,6R-dihydroxy-7E,9E,11Z,14Z-eicosatetraenoic acid
  • 5S,6R-dihydroxy-7E,9E,11Z,14Z-eicosatetraenoic acid
5(S),6(R)-DiHETE
Formula C20H32O4
Exact Mass 336.23005951199997
Average Mass 336.46567999999996
SMILES C(CC=CCC=CC=CC=C[C@@H](O)[C@@H](O)CCCC(O)=O)CCC
Physicochemical Information
Soluble in ethanol.
5S,6R-DiHETE is a dihydroxy polyunsaturated fatty acid and a nonenzymatic hydrolysis product of leukotriene A 4 .
Mouse liver cytosolic epoxide hydrolase catalyzes the conversion of LTA to 5,6-DiHETE Haeggstrom_J et al..
5(S),6(R)-DiHETE is a weak LTD 4 receptor agonist in guinea pig lung membranes Muller_A et al.. It induces guinea pig ileum contraction with an ED value of 1.3 mu M.
Spectral Information
Mass Spectra
UV Spectra λ max:273nm ε :40,000
IR Spectra
NMR Spectra
Other Spectra
Chromatograms
Reported Metabolites, References
Biospecies ID Compound Name Reference Comment
n.a. LBF20406HO07 See above. Haeggstrom_J et al. 1988
n.a. LBF20406HO07 See above. Muller_A et al. 1989