LBF20307PG06

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Fatty acid (脂肪酸)

Glycerolipid (グリセロ脂質)

Sphingolipid (スフィンゴ脂質)

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Upper classes: LB LBF

IDs and Links
LipidBank	XPR1768
LipidMaps	LMFA03010086
CAS
KEGG	{{{KEGG}}}
KNApSAcK	{{{KNApSAcK}}}
mol	LBF20307PG06

16,16-dimethyl Prostaglandin A2
Structural Information
Systematic Name	9-Oxo-15R-hydroxy-16,16-dimethyl-prosta- (5-cis,10,13-trans) -trien-1-oic acid
Common Name	16,16-dimethyl Prostaglandin A2 9-Oxo-15R-hydroxy-16,16-dimethyl-prosta- (5Z,10,13E) -trien-1-oic acid
Symbol
Formula	C22H34O4
Exact Mass	362.24570957599997
Average Mass	362.50296000000003
SMILES	C(C(C)(C)[C@H](C=C[C@@H](C=1)[C@@H](CC=CCCCC(O)=O)C(C1)=O)O)CCC
Physicochemical Information
Melting Point
Boiling Point
Density
Optical Rotation
Refractive Index
Solubility	16,16-dimethyl Prostaglandin A2 is soluble in organic solvents (i.e. methyl acetate, DMSO, ethanol) at least 50 mg/ml and also in aqueous buffers or isotonic saline at least 2.4 mg/ml. But in basic solutions (pH >7.4) 16,16-dimethyl Prostaglandin A2 will be converted into 16,16-dimethyl Prostaglandin PGB2.
Source
Chemical Synthesis
Metabolism
Biological Activity	16,16-dimethyl Prostaglandin A2 shows inhibitory effect on the proliferation of Sendai virus in monkey cells. Tanaka_T et al. 16,16-dimethyl Prostaglandin A2 significantly increases mouse survival against nfection with influenza A by an average of 40% and decreases virus titers in the lungs without alteration of the host immune response. Santoro_MG et al.
Genetic Information
Note
Spectral Information
Mass Spectra
UV Spectra	λ max=215nm ε 216=12200
IR Spectra
NMR Spectra
Other Spectra
Chromatograms

Reported Metabolites, References
Biospecies ID Compound Name Reference Comment n.a. LBF20307PG06 See above. Santoro_MG et al. 1988 n.a. LBF20307PG06 See above. Tanaka_T et al. 1987