LBF20207PG43

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Upper classes: LB LBF



8-iso Prostaglandin E2
LBF20207PG43.png
Structural Information
9-Oxo- (11α,15S) -dihydroxy- (8β) -prosta- (cis-5,trans-13) -dien-1-oic acid
  • 8-iso Prostaglandin E2
  • 9-Oxo- (11α,15S) -dihydroxy- (8β) -prosta- (5Z,13E) -dien-1-oic acid
Formula C20H32O5
Exact Mass 352.224974134
Average Mass 352.46508
SMILES C(CC[C@H](O)C=C[C@H]([C@@H]1CC=CCCCC(O)=O)[C@@H](CC1=O)O)CC
Physicochemical Information
8-iso PGE2 inhibits U-46619 or I-BOP-induced platelet aggregation with IC50 values of 0.5 and 5 mu M. Longmire_AW et al. 8-iso PGE2 is also reported to decrease 80% of the GFR and renal plasma flow without affecting blood pressure in infusing into the renal artery of rats. Pace-Asciak_C
Spectral Information
Mass Spectra
UV Spectra
IR Spectra
NMR Spectra
Other Spectra
Chromatograms
Reported Metabolites, References
Biospecies ID Compound Name Reference Comment
n.a. LBF20207PG43 See above. Pace-Asciak_C 1976